• Estas organizaciones decidieron dejar fuera los temas

  2018-11-15

  

  Estas organizaciones decidieron dejar fuera los temas de homosexualidad y aborto, porque no estaban en el programa oficial; fue parte de una acción que apeló al derecho positivo, pues citaron todo un andamiaje jurídico nacional e internacional, ya que la educación sexual laica está respaldada en el

• br Material and methods A draft of

  2018-11-14

  

  Material and methods A draft of the questionnaire was validated based on input from experts drawn from the research domains that contributed to the content of the questionnaire, and the questionnaire was then tested for comprehension and clarity with a group of university students from a range o

• br Results br Discussion Here we describe the role

  2018-11-14

  

  Results Discussion Here we describe the role for histone demethylases KDM4A and KDM4C in the epigenetic regulation of mESC differentiation to endothelial cells. We showed that KDM4A and KDM4C targeted the tri-methyl histone 3 lysine 9 (H3K9me3), a known repressive marker of gene regulation (Bl

• br Problem setting PS M V a presenilin model implying

  2018-11-14

  

  Problem setting PS1-M146V, a presenilin model implying the presence of a mutation in the gene encoding the presenilin protein [7]; APPKI, an amyloid model implying the presence of a mutation in the gene encoding APP [9]. Recently, our laboratory has developed one more model which, in reverse tr

• The first bleeding risk prediction

  2018-11-14

  

  The first bleeding risk prediction score (ORBI score) was published in 1998 and it was developed in patients newly started on warfarin after hospitalisation for venous thromboembolism (Beyth et al., 1998). Since then various bleeding risk scores have been described but only four (HAEMORR2AGES (Gage

• br Discussion Standardized case ascertainment based on pre d

  2018-11-14

  

  Discussion Standardized case ascertainment based on pre-defined case definitions has been shown to be reproducible and consistent (Rath et al., 2010; Muehlhans et al., 2012). The retrospective classification of clinical cases however, is often challenged by missing data in medical records, thus l

• br CRISPR Cas Tips and Tricks

  2018-11-14

  

  CRISPR Cas9 Tips and Tricks Dario Lupianez and Malte Spielmann (Berlin, Germany) held an engaging workshop titled CRISPR Cas9 tips and tricks. The aim was to demonstrate how this genome editing technology can be utilized in embryonic stem TASIN-1 (ESCs) to produce genomic structural variations (

• The authors addressed this question using a meta analytic

  2018-11-14

  

  The authors addressed this question using a meta-analytic approach involving 15 studies that examined more than 12,000 smokers (). The study found that there were no differences in the benefits of quitting based on CHRNA5 allelic status. Consistent with many previous studies the benefits of quitting

• There are additional important noteworthy points Although

  2018-11-14

  

  There are additional important noteworthy points. Although both retinal pigment epithelial tsa inhibitor (RPE) and endothelial cells showed glucose induced reduction of miR15a and associated alteration, overexpression of miR15a in the endothelial cells (as Tie2 is not expressed in the RPE) prevente

• The observation of increases in plasma BPG in the

  2018-11-14

  

  The observation of increases in plasma 2,3-BPG in the TBI patients, which was unrelated to the patient outcome, is difficult to interpret for two reasons. First, blood concentrations of 2,3-BPG are dominated by the concentration of this metabolite in red blood cells (RBCs), where it acts as an allos

• Potential associations between epigenetic regulation of

  2018-11-14

  

  Potential associations between epigenetic regulation of HPA axis genes and clinical outcomes still remain relatively unmapped, as only DNA methylation of NR3C1, HSD11β2, and FKBP5 has been studied in direct relation to risk for any human disease, with the majority of research focusing on epigenetic

• BCG has been integrated into the Expanded Immunization

  2018-11-14

  

  BCG has been integrated into the Expanded Immunization Program of WHO since 1974 and neonatal vaccination with BCG is still used to prevent TB in countries with a high burden of TB (Marais et al., 2016). Correspondingly, adolescents and adults with LTBI always occur epidemiologically following inocu

• br Discussion Genome wide analyses of the mammalian

  2018-11-14

  

  Discussion Genome-wide analyses of the mammalian transcriptome revealed that lncRNAs is pervasively transcribed in the genome and accumulating studies have demonstrated that lncRNAs as novel regulatory molecule plays critical roles in mammalian development [1,2], but little is known about the pot

• br Value of the data br Experimental design

  2018-11-14

  

  Value of the data Experimental design, materials and methods Specifications table Value of the data Data, experimental design, materials and methods Materials and methods Data In summary, a total of 74,433 peptides corresponding to 9247 protein groups were identified as the new vers

• Recent research has highlighted the role of callous unemotio

  2018-11-13

  

  Recent research has highlighted the role of callous-unemotional (CU) traits, characterised by a lack of guilt, remorse and empathy, in increased risk for persistent antisocial behaviour and adult psychopathy (Barry et al., 2000; Frick et al., 2003; Viding, 2004; Frick and White, 2008; Frick et al.,

16103 records 1051/1074 page Previous Next First page 上5页 10511052105310541055 下5页 Last page